Sero-prevalence and Risk Factors for Hepatitis A Virus Infection among Pregnant Women at the Samandin Medical Center, Ouagadougou, Burkina Faso

Main Article Content

Rouamba Poda Somda Hortense
Ouoba Jean Bienvenue
Traoré Kuan Abdoulaye
Ouoba Bruno Lalidia
Kagambéga Asséta
Roques Pierre
Barro Nicolas

Abstract

Aims: This study determined prevalence and possible risk factors associated with HAV infection and compared Immunochromatography (IgG) rapid point of care test with standard ELISA test for diagnosis.


Study Design:  Cross sectional epidemiological survey.


Place and duration of Study: The study was carried out at the Samandin Medical Center (Ouagadougou, Burkina Faso), from July 2017 to December 2017.


Methodology: A total of 180 pregnant women were recruited at the Samandin Medical Center. Anti-HAV IgM and IgG detection tests were performed using AccuDiag™ HAV ELISA kit (Calabasas, CA, USA) and SD BIOLINE HAV IgG/IgM Rapid Diagnostic Test (Gyeonggi-do, Korea).


Results: IgG anti-HAV antibodies (AccuDiag Elisa) were found with a prevalence of 88.9% (160/180) and Anti-HAV IgM were 1.1% (2/180). Of the 160 AccuDiag HAV IgG positive samples, 44.4% (80/180) tested positive using SD BIOLINE Diagnostics HAV IgG. Regarding risk factors, 86.9% (86/99) of the IgG positive women were illiterate; 90.7% (39/43) lived mostly in peripheral areas; 89.2% (74/83) were household workers and 88.6% (93/105) used fountain water.


Conclusion: Our results demonstrated poor agreement between the assays tested, which are consistent with previous reports demonstrating significant variability between HAV ELISA and RDT HAV. Moreover, the detection of HAV specific IgM antibodies in two asymptomatic pregnant women signaled the current circulation of HAV in this area.

Keywords:
Hepatitis A virus, pregnant women, socio-economic and demographic conditions, Burkina Faso

Article Details

How to Cite
Hortense, R., Bienvenue, O., Abdoulaye, T., Lalidia, O., Asséta, K., Pierre, R., & Nicolas, B. (2019). Sero-prevalence and Risk Factors for Hepatitis A Virus Infection among Pregnant Women at the Samandin Medical Center, Ouagadougou, Burkina Faso. Journal of Advances in Biology & Biotechnology, 21(3), 1-9. https://doi.org/10.9734/jabb/2019/v21i330095
Section
Original Research Article

Article Metrics


References

Ryan KJ, Ray CG. Medical microbiology. McGraw Hill. 2004;4:370.

Hamza H, Abd-Elshafy DN, Fayed SA, Bahgat MM, El-Esnawy NA, Abdel-Mobdy E. Detection and characterization of hepatitis A virus circulating in Egypt. Archives of virology. 2017;162(7):1921-31.

Vaughan G, Rossi LMG, Forbi JC, de Paula VS, Purdy MA, Xia G, et al. Hepatitis A virus: Host interactions, molecular epidemiology and evolution. Infection, Genetics and Evolution. 2014;21:227-43.

Naoumov NV. Hepatitis A and E. Medicine. 2007;35(1):35-8.

Keystone JS, Hershey JH. The underestimated risk of hepatitis A and hepatitis B: benefits of an accelerated vaccination schedule. International Journal of Infectious Diseases. 2008;12(1):3-11.

Wang X, Ren J, Gao Q, Hu Z, Sun Y, Li X, et al. Hepatitis A virus and the origins of picornaviruses. Nature. 2015;517(7532):85.

Malhotra B, Kanwar A, Reddy PJ, Chauhan A, Tiwari J, Bhargava S, et al. Molecular characterization of hepatitis A virus from children hospitalized at a tertiary care centre in northwest India. The Indian journal of medical research. 2018;147(5):507.

Lin KY, Chen GJ, Lee YL, Huang YC, Cheng A, Sun HY, et al. Hepatitis A virus infection and hepatitis A vaccination in human immunodeficiency virus-positive patients: A review. World Journal of Gastroenterology. 2017;23(20):3589.

Lai M, Chopra S. Hepatitis A virus infection in adults: Epidemiology, clinical manifestations, and diagnosis. 2018;13.

Franco E, Meleleo C, Serino L, Sorbara D, Zaratti L. Hepatitis A: Epidemiology and prevention in developing countries. World journal of hepatology. 2012;4(3):68.

Jacobsen K, Koopman J. The effects of socioeconomic development on worldwide hepatitis A virus seroprevalence patterns. International journal of epidemiology. 2005; 34(3):600-9.

WHO. Hepatitis A; 2014.
Available:http://wwwwhoint/mediacentre/factsheets/fs328/en/

Ceyhan M, Yildirim I, Kurt N, Uysal G, Dikici B, Ecevit C, et al. Differences in hepatitis A seroprevalence among geographical regions in Turkey: A need for regional vaccination recommendations. Journal of Viral Hepatitis. 2008;15:69-72.

Kiyohara T, Sato T, Totsuka A, Miyamura T, Ito T, Yoneyama T. Shifting seroepidemiology of hepatitis A in Japan, 1973–2003. Microbiology and Immunology. 2007;51(2):185-91.

Hofmeister MG, Foster MA, Teshale EH. Epidemiology and transmission of hepatitis A virus and hepatitis E virus infections in the United States. Cold Spring Harbor Perspectives in Medicine. 2019;9(4): a033431.

Fiore AE, Wasley A, Bell BP. Prevention of hepatitis A through active or passive immunization: Recommendations of the Advisory Committee on Immunization Practices (ACIP). Morbidity and Mortality Weekly Report: Recommendations and Reports. 2006;55(7):1-CE-4.

Biziagos E, Divizia M, Crance J, Deloince R, Panà A. Techniques de Mise en Evidence des Virus des Hepatitis; 1991.

Karimi A, Imani-Rastabi R, Moezzi M, Moradi M-T. Hepatitis a seroprevalence and associated risk factors: A communitybased cross-sectional study in Shahrekord, Iran. Archives of Clinical Infectious Diseases. 2016;11(1).

Cho GJ, Kim YB, Kim SM, Hong HR, Kim JH, Seol H-J, et al. Hepatitis A virus infection during pregnancy in Korea: Hepatitis A infection on pregnant women. Obstetrics & gynecology science. 2013; 56(6):368-74.

Chaudhry SA, & Koren, G. Hepatitis A infection during pregnancy. Canadian Family Physician Medecin de Famille Canadien. 2015;61(11):2.

Watson JC, Fleming DW, Borella AJ, Olcott ES, Conrad RE, Baron RC. Vertical transmission of hepatitis A resulting in an outbreak in a neonatal intensive care unit. Journal of Infectious Diseases. 1993; 167(3):567-71.

Urganc N, Arapoglu M, Akyldz B, Nuhoglu A. Neonatal cholestasis resulting from vertical transmission of hepatitis A infection. The Pediatric Infectious Disease Journal. 2003;22(4):381-2.

Motte A, Blanc J, Minodier P, Colson P. Acute hepatitis A in a pregnant woman at delivery. International Journal of Infectious Diseases. 2009;13(2):e49-e51.

Simpore J, Ouermi D, Ilboudo D, Kabre A, Zeba B, Pietra V, et al. Aetiology of acute gastro-enteritis in children at Saint Camille Medical Centre, Ouagadougou, Burkina Faso. Pakistan Journal of Biological Sciences: PJBS. 2009;12(3):258-63.

Traoré K, SHR, AST, PR, Barro N. Viral hepatitis in West African Country, Burkina Faso. Advance Tropical Medicine and Public Health International. 2015;5(4):17.

Traoré KA, Rouamba H, Nébié Y, Sanou M, Traoré AS, Barro N, et al. Seroprevalence of fecal-oral transmitted hepatitis A and E virus antibodies in Burkina Faso. PloS one. 2012;7(10):e48125.

Lam S, Devine P. Evaluation of capture ELISA and rapid immunochromatographic test for the determination of IgM and IgG antibodies produced during dengue infection. Clinical and Diagnostic Virology. 1998;10(1):75-81.

Boyce RM, Muiru A, Reyes R, Ntaro M, Mulogo E, Matte M, et al. Impact of rapid diagnostic tests for the diagnosis and treatment of malaria at a peripheral health facility in Western Uganda: An interrupted time series analysis. Malaria Journal. 2015; 14(1):203.

Dussaix E, Mackiewicz V, Roque-Afonso A. Epidemiology of hepatitis A: What about in 2007?. Virology. 2007;11(5):361.

Sadlier C, O’Rourke A, Carr A, Bergin C. Seroepidemiology of hepatitis A, hepatitis B and varicella virus in people living with HIV in Ireland. Journal of Infection and Public Health. 2017;10(6):888-90.

Lee YL, Lin KY, Cheng CY, Li CW, Yang CJ, Tsai MS, et al. Evolution of hepatitis A virus seroprevalence among HIV-positive adults in Taiwan. PloS one. 2017;12(10): e0186338.

Doni NY, Şimşek Z, Gürses G, Zeyrek FY, Akbaba M. The knowledge and high seroprevalence of hepatitis A in a high-risk group (agricultural reproductive-aged women) in the southeastern region of Turkey. Turkish Journal of Medical Sciences. 2017;47(4):1055-60.

Kamal SM, Mahmoud S, Hafez T, EL-Fouly R. Viral hepatitis A to E in South Mediterranean countries. Mediterranean Journal of Hematology and Infectious Diseases. 2010;2(1).

Qiao Y, Sui Z, Hu G, Cao H, Yang G, Li Y, et al. Comparison of concentration methods for detection of hepatitis A virus in water samples. Virologica Sinica. 2016;31(4):331-8.

Saberifiroozi M. Hepatitis A virus infection: Is it an important hazard to public health?: hazards of HAV for public health. Hepatitis Monthly. 2011;11(4):235.

Bura M, Michalak M, Chojnicki MK, Kowala-Piaskowska A, Mozer-Lisewska I. Viral hepatitis A in 108 adult patients during an eight-year observation at a single center in Poland. Adv Clin Exp Med. 2015;24:829-36.

Pinheiro RS, Araújo LAd, Caetano KAA, Matos MAd, Carneiro MAdS, Teles SA. Intermediate endemicity of hepatitis A virus infection in rural settlement projects of Southwest Goiás, Brazil. Arquivos de Gastroenterologia. 2015;52(3):200-3.

Jacobsen KH. Hepatitis A virus in West Africa: Is an epidemiological transition beginning? Nigerian Medical Journal: Journal of the Nigeria Medical Association. 2014;55(4):279.

Rodriguez-Lazaro D, Cook N, Ruggeri FM, Sellwood J, Nasser A, Nascimento MSJ, et al. Virus hazards from food, water and other contaminated environments. FEMS Microbiology Reviews. 2012;36(4):786-814.

Ahmad T, Adnan F, Nadeem M, Kakar SJ, Anjum S, Saad A, et al. Assessment of the risk for human health of enterovirus and hepatitis A virus in clinical and water sources from three metropolitan cities of Pakistan. Ann Agric Environ Med. 2018; 25(4):708-13.

Elinav E, Ben–Dov IZ, Shapira Y, Daudi N, Adler R, Shouval D, et al. Acute hepatitis A infection in pregnancy is associated with high rates of gestational complications and preterm labor. Gastroenterology. 2006; 130(4):1129-34.

Neffatti H, Lebraud P, Hottelet C, Gharbi J, Challouf T, Roque-Afonso AM. Southern Tunisia: A still high endemicity area for hepatitis A. PloS one. 2017;12(4): e0175887.

Ranger-Rogez S, Alain S, Denis F. Hepatitis viruses: Mother to child transmission. Pathologie-Biologie. 2002; 50(9):568-75.