Prevalence of Enteropathogenic Escherichia coli and Rotavirus Antigen among Diarrheic Children Attending Selected Hospitals in Abeokuta, Nigeria: A Comparative Study
Journal of Advances in Biology & Biotechnology,
Background: Diarrheal infections are one of the leading causes of sickness and death all over the world. It is the second-most common cause of under-five mortality, accounting for over half a million deaths annually. In Abeokuta, the etiology of diarrheagenic bacteria and diarrheagenic viruses has not been well studied.
Objective: To determine the prevalence of Enteropathogenic Escherichia coli and Rotavirus Antigen among Diarrheic Children attending Selected Hospitals in Abeokuta, Nigeria: A Comparative study.
Methods: A total of 315 stool samples were collected from children 0–5 years of age across three selected hospitals. With a wooden spatula, 5ml of fecal sample was scooped and decanted into clean, labeled screw-capped tubes. Rotavirus antigen screening was performed according to the manufacturers’ instructions, while EPEC screening was performed using cultural, biochemical, and stereotyping methods.
Results: From the sample screening performed, 30 (37.04%) were EPEC positive, whereas 51 (62.96%) were positive for rotavirus. Dissemination of children based on ageshowed that children between 7–12 months had the most elevated predominance of Rotavirus infection 17 (33.33%) while the lowest predominance was observed in children between 0–2 months 4 (7.84%). Furthermore, the highest predominance of EPEC diseases was observed in children between 7–12 months 12 (40%) and the lowest predominance in children between 19–24 months 2 (6.67%).
Conclusion: This study had demonstrated a higher prevalence of Rotavirus infection as compared to EPEC diseases among Diarrheic Children within the study location.
- Enteropathogenic Escherichia coli ( EPEC )
- diarrheic children
How to Cite
Abba K, Sinfield R, Hart CA, Garner P. Pathogens associated with persistent diarrhoea in children in low and middle income countries: systematic review. BMC Infect Dis. 2009;9:88.
Lee JB, Kim SK, Yoon JWK, Jang Won Y. Pathophysiology of enteropathogenic Escherichia coli during a host infection. J Vet Sci. 2022;23(2):28.
GBD. Diarrhoeal DiseaseCollaborators. Estimates of the global, regional, and national morbidity, mortality, and aetiologies of diarrhoea in 195 countries: A systematic analysis for the Global Burden of Disease Study. Lancet Infect Dis. 2016;10(18):30362-1.
Okeke IN. Diarrheagenic Escherichia coli in sub-Saharan Africa: status, uncertainties and necessities. J Infect Dev Ctries. 2009;3(11):817-42.
Arora D, Salesh KJ, Ghai TR. Gene action for some biochemical traits in Okra. Veg Sci. 2008;35(2):180-4.
Olanipekun OO. Prevalence of Enteropathogenic Escherichia coli in children with diarrhoea attending Jos University Teaching Hospital [MSc thesis]. Jos: University of Jos; 1996.
Ifeanyi CI. Cajetan1 IRN, Akpa AC, Ikenech NF. Sci J. Enteric Bacteria Pathogens Associated With Diarrhoea of Children in the Federal Capital Territory Abuja, Nigeria. New York. 2010;3(1): 62-9.
Cho SH, Kim JH, Kim JC. Survellaince of bacteria pathogens associated with acute diarrheal diseases in the Republic of Korea during one year. J Micbiology. 2006;44:327-35.
Jafari F, Leila S, Mohammad H, Siavash S, Mohammad RZ. Acute diarrhea due to Enteropathogenic bacteria in patients at Hospital in Tehran. Jpn J Infect Dis. 2008;6:269-73.
Svenungsson B, Lagergren A, Ekwall E, Evengård B, Hedlund KO, Kärnell A et al. Enteropathogens in adult patients with diarrhea and healthy control subjects: A 1- year prospective study in a Swedish Clinic for Infectious Diseases. Clin Infect Dis. 2000;30(5):770-8.
Olaniran O, Japheth O, Asinwa H, Olajokun-Hassan H, Awoyeni E, Adekunle O. Isolation and evaluation of E. coli in diarrhoeic stool samples from children in Ile-Ife, Nigeria. J Dis Glob Health. 2015;4(4):145-51.
Abstract View: 32 times
PDF Download: 16 times