Notifications of Leptospirosis in the State of Ceará - Brazil, from 2013 to 2019: Profile of Cases and Factors Associated with the Incidence

Renara Régia Rocha Carneiro

Pharmacist Hospital in the Northern Region of the City of Sobral, State of Ceará, Brazil.

Guilherme Mendes Prado

Pharmacy Course Teacher, University Center INTA, Sobral-CE, Brazil.

Júlio César Sousa Prado *

Microbiology Laboratory, Faculty of Medicine, Federal University of Ceará, Sobral-CE Campus, Brazil.

Jardna Diniz Macêdo

Biomol, Department of Biochemistry and Molecular Biology at the Federal University of Ceará, City of Fortaleza, State of Ceará, Brazil.

*Author to whom correspondence should be addressed.


Abstract

Objective: This study proposes an epidemiological analysis and distribution of human cases of leptospirosis reported in the State of Ceará, from 2013 to 2019.

Methods: Descriptive study, with data on leptospirosis accidents reported in the Notifiable Diseases Information System between 2013 and 2019.

Results: 344 cases and 24 deaths were reported, with emphasis on the second two months (41%), corresponding to an average annual incidence of 0.54/105 inhabitants and a fatality rate equal to 2.2% per year, directly related to rainfall rates. Of those affected by the disease, 72% were aged 20 to 59, 76% were men, 88% considered themselves black, 39% were residents of urban areas and 59% did not report their education; 87% were diagnosed using clinical-laboratory criteria and 76% were cured.

Conclusion: There was an increase in reports of leptospirosis associated with rainfall, mainly affecting the economically active population, most of whom live on the social margins.

Keywords: Leptospira, descriptive epidemiology, neglected diseases, socioeconomic factors


How to Cite

Carneiro , R. R. R., Prado , G. M., Prado , J. C. S., & Macêdo , J. D. (2023). Notifications of Leptospirosis in the State of Ceará - Brazil, from 2013 to 2019: Profile of Cases and Factors Associated with the Incidence. Journal of Advances in Biology & Biotechnology, 26(9), 40–48. https://doi.org/10.9734/jabb/2023/v26i9655

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References

Melo TF, Peconick AP. The characteristics of Leptospira spp: A literature review. Scire Salutis. Jun-Sep 2019 [cited 2020 May 12];9(3):1-7. Available:https://sustenere.co/index.php/sciresalutis/article/view/CBPC2236-9600.2019.003.0001/1764. doi: 10.6008/CBPC2236-9600.2019.003.0001

Duarte JL, Giatti JJ. Incidence of leptospirosis in a capital of the Brazilian Western Amazon and its relationship with climate and environmental variability, between 2008 and 2013. Epidemiol. Serve. Health. 2019[cited 2020 May 12];28(1):1-9.

Available:https://www.scielo.br/pdf/ress/v28n1/2237-9622-ress-28-01-e2017224.pdf. DOI: 10.5123/S1679-49742019000100009

Fernandes ARF, Fernandes AG, Araújo VEJA, Higino SSS, Silva MLCR, Alves CJ, et al. Seroepidemiology of canine leptospirosis in the metropolitan region of Natal, State of Rio Grande do Norte. Braz. J. Veterinarian. Res. Anima. Sci, São Paulo[Internet]. 2013 [cited 2020 May 14];50(3):226-232. Available:https://www.researchgate.net/publication/276416661_Soroepidemiologia_da_leptospirose_canina_na_regiao_metropolitana_de_Natal_estado_do_Rio_Grande_do_Norte.

DOI: 10.11606/issn.1678-4456.v50i3p226-232

Negrão DD, Gonçalves D. Incidence of leptospirosis in stray dogs collected at the control and zoonosis center of Curitiba. Electronic Magazine of the Evangelical Faculty of Paraná [Internet]. 2012 Oct-Dec [cited on 29 May];2(4):63-68.

Available:https://docplayer.com.br/38217032-trabalho-de-conclusao-de-curso-incidencia-de-leptospirose-em-caes-errantes-acoldos-no-centro-de-controle-e-zoonoses -de-curitiba.html.

Ministry of Health (BR). Health surveillance secretariat. General coordination for the development of epidemiology in services. Health Surveillance Guide: single volume. 3rd ed. Brasília: Ministry of Health; 2019.

Ministry of Health (BR). Department of health surveillance. Department of communicable disease surveillance. Leptospirosis: Diagnosis and clinical management. Brasília: Ministry of Health; 2014. Available:http://www.saude.gov.br/images/pdf/2015/janeiro/16/Leptospirose-diagnostico-manejo-clinico.pdf

Soek K. Canine leptospirosis – review Curitiba: UTP; 2012 [cited on May 10, 2020];58.

Available:https://tcconline.utp.br/leptospirose-canina-revisao/

Brazilian Institute of Geography and Statistics. Ceará. 2019. Rio de Janeiro: Brazilian Institute of Geography and Statistics; 2019 [data unknown] [cited 2020 May 30]. Available:https://cidades.ibge.gov.br/brasil/ce/panorama

Camurça CES, Alencar AB, Cidade EC, Ximenes VM. Psychosocial implications of drought on the lives of residents of a municipality in the rural area of northeastern Brazil. Advances in Latin American Psychology, Bogotá [Internet]. 2016 [cited May 24, 2020];34(1):117-128. Available:http://www.scielo.org.co/pdf/apl/v34n1/v34n1a09.pdf.

DOI: dx.doi.org/10.12804/apl34.1.2016.08

Brazil. Civil House. Law No. 12,288, of July 20, 2010. Establishes the racial equality statute; amends Laws No. 7,716, of January 5, 1989, No. 9,029, of April 13, 1995, No. 7,347, of July 24, 1985, and No. 10,778, of November 24, 2003. Official Gazette of the Union, Brasília (DF), 20 Jul 2010 [cited 27 May 2020]; Section 1:144.

Available:http://www.planalto.gov.br/ccivil_03/_Ato2007-2010/2010/Lei/L12288.htm

Cearense Foundation of Meteorology and Water Resources. Rain Calendar in the State of Ceará. 2020. Ceará: Cearense Foundation of Meteorology and Water Resources; 2020 [cited on May 24, 2020]. Available:http://funceme.br/app/calendario/produto/ceara/media/mensal

Ministry of Health (BR). SUS IT Department - DATASUS [Internet]. 2014. Brasília: Ministry of Health; 2014 [cited on May 12, 2020]. Available:http://datasus.saude.gov.br/

Ministry of Health (BR). National Health Council. Resolution no. 510, of April 7, 2016. Deals with guidelines and regulatory standards for research in human and social sciences. Official Gazette of the Union, Brasília (DF) [Internet]. May 24, 2016 [cited May 30, 2020]. Available:http://conselho.saude.gov.br/resolucoes/2016/Reso510.pdf

Sousa JA. Analysis of the spatio-temporal relationship between the occurrence and occurrence of leptospirosis in Fortaleza – CE from 2010 to 2015 [dissertation]. Fortaleza (CE): Federal University of Ceará; 2017.

Secretary of Health Surveillance. Ministry of Health. Leptospirosis: Epidemiological situation in Brazil from 2007 to 2016. Epidemiological Bulletin; 2018. Available:https://portalarquivos2.saude.gov.br/images/pdf/2018/outubro /25/2018-033-Leptospirosis-situa ----o-epidemiol--gica-do-Brasil-no-per--odo-de-2007-to-2016-publica--ao.pdf.

Magalhães VS, Acosta LMW. Human leptospirosis in Porto Alegre, Rio Grande do Sul, from 2007 to 2013: Characterization of confirmed cases and spatial distribution. Epidemiol. Serv. Health. 2019 [cited on: 2020 May 26];28(2):1-12. Available:https://www.scielo.br/pdf/ress/v28n2/2237-9622-ress-28-02-e2018192.pdf. DOI:10.5123/S1679-49742019000200019

Sethi S, Shrama N, Kakkar N, Taneja J, Chatterjee SS, Banga SS, et al. Increasing trends of leptospirosis in Northern India: a clinical-epidemiological study. PLoS Negl Trop Dis. 2010 Feb [cited in 2020 Jun 10];4(1). Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797087/. DOI: 0.1371/journal.pntd.0000579

Haake DA, Levett PN. Leptospirosis in humans. Curr Top Microbiol Immunol [Internet]. 2015 nov [cited on 11 Jun 2020];387:65-97. Available:https:// www.ncbi.nlm.nih.gov/pubmed/25388133.

DOI:10.1007/978-3-662-45059-8_5

Pereira CAR. Social cost of leptospirosis in Brazil and the effect of extreme rainfall in Nova Friburgo on the increase in cases of the disease [dissertation]. Rio de Janeiro (RJ): Sergio Arouca National School of Public Health; 2014.

Souza VMM, Arsky MLNS, Castro APB, Araújo WN. Potential years of life lost and hospital costs of leptospirosis in Brazil. Rev Saúde Públ [Internet]. 2011 Dec [cited in 2020 Jun 16];45(6):1001-8. Available:https://www.scielo.br/pdf/rsp/v45n6/3013.pdf.

Available:http://dx.doi.org/10.1590/S0034-89102011005000070

Lara JM, Zuben AV, Costa JV, Donalisio MR, Francisco PMSB. Leptospirosis in the city of Campinas, São Paulo, Brazil: 2007 to 2014. Rev Bras Epidemiol. 2019 Apr [cited in 2020 Jun 8];22:1-13.

Available:https://scielosp.org/article/rbepid/2019.v22/e190016/#. DOI:10.1590/1980-549720190016

Nahas MIP, Moura ASA, Carvalho RC, Heller L. Inequality and discrimination in access to water and sanitation in the Metropolitan Region of Belo Horizonte, Minas Gerais, Brazil. Cad. Public Health. 2019 [cited in 2020 Jun 09]; 35(4). Available:https://www.scielo.br/pdf/csp/v35n4/1678-4464-csp-35-04-e00100818.pdf. https://doi.org/10.1590/0102-311x00100818

Pelissari DM, Maia-Elkhoury ANS, Arsky MLNS, Nunes ML. Systematic review of factors associated with leptospirosis in Brazil, 2000-2009. Epidemiol. Serv. Health [Internet]. 2011 Oct-Dec [cited on 17 Jun 2020];20(4):565-574.

Available:http://scielo.iec.gov.br/pdf/ess/v20n3/v20n4/v20n4a16.pdf. doi: 10.5123/S1679-49742011000400016

Vasconcelos CH, Fonseca FR, Lise MLZ, Arsky MLNS. Environmental and socioeconomic factors related to the distribution of leptospirosis cases in the State of Pernambuco, Brazil, 2001–2009. Cad. Health Collect. 2012 Jan [cited in 2020 May 13];20(1):49-56. Available:http://www.cadernos.iesc.ufrj.br/cadernos/images/csc/2012_1/artigos/CSC_v20n1_49-56.pdf.

Coelho AGV, Alves IJ, Farias VLV. Epidemiological profile of leptospirosis cases in the Metropolitan Region of Baixada Santista (SP), Brazil. Bol. epidemiol. paul. 2019 [cited in 2020 Jun 5];16(183-184):3-14.

Available:http://docs.bvsalud.org/biblioref/2019/10/1023295/151833-14.pdf.

Silva FJ, Silva GCP, Loffler SG, Brihuega B, Samartino LE, Alarcon MFF, et al. Isolation of Leptospira spp. from a man living in a rural area of the Municipality of Cruz Alta, RS, Brazil. Rural Science. 2015 Jan [cited in 2020 Jun 09] 45(1):47-51. Available:https://www.scielo.br/pdf/cr/v45n1/0103-8478-cr-00-00-cr20140253.pdf. https://doi.org/10.1590/0103-8478cr20140253