Antimicrobial and Anti-inflammatory Activities of Some Marine Brown and Red Algal Species Collected from Safaga Seashore, Red Sea, Egypt
Neveen Abdel-Raouf
Department of Botany and Microbiology, Faculty of Science, Beni-Suef University, 62514, Egypt
Hossam M. Hassan *
Department of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, 62514, Egypt and Department of Pharmacognosy, Faculty of Pharmacy, Nahda University, Beni-Suef, 62514, Egypt
Yara Khayri
Department of Botany and Microbiology, Faculty of Science, Beni-Suef University, 62514, Egypt
Abeer Moawwad
Department of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, 62514, Egypt
Waleed A. Mohamed
Department of Biochemistry, Kasr El-Eini Teaching Hospitals, Cairo University, Egypt
Ibraheem B. M. Ibraheem
Department of Botany and Microbiology, Faculty of Science, Beni-Suef University, 62514, Egypt
*Author to whom correspondence should be addressed.
Abstract
Aims: Estimation of the biological activities of 3 algal crude extracts for anti-inflammatory and antimicrobial activities.
Methodology: Three marine algae were collected from Safaga seashores, the Red Sea in Egypt, extracted using 70% hydroalcoholic methanol. The antimicrobial activities were carried out using agar disc diffusion method, in addition to the In vivo anti-inflammatory investigation.
Results: The three algal extracts showed significant antimicrobial activity against most of the microbial strains. Moreover, the three extracts showed explicit anti-inflammatory effects by determination different inflammation parameters as Superoxide dismutase (SOD), Malondialdehyde (MDA), Catalase, Glutathione (GSH), Interleukin-6(IL-6) and Tumor necrosis factor ( TNF-α).
Conclusion: The Three algae, has a notable antimicrobial and anti-inflammatory activity, that may be due to their unique bioactive secondary metabolites pattern.
Keywords: Marine algae, antimicrobial, anti-inflammatory, Cystoseira barbata, Hydroclathrus clathratus, Liagora farinosa