Journal of Advances in Biology & Biotechnology

Genomic innovations have revolutionized the field of wheat breeding by providing advanced tools to enhance its biofortification and overall productivity. This comprehensive review synthesizes recent developments in wheat genomics, focusing on the integration of various approaches such as genome-wide association studies (GWAS), marker-assisted selection (MAS), and quantitative trait locus (QTL) mapping. These genomic techniques have significantly advanced our understanding of the genetic basis underlying key traits, facilitating the development of wheat varieties with improved nutritional profiles and agronomic characteristics. Association mapping, leveraging natural variation within wheat populations, has identified numerous genetic loci associated with important traits, including grain quality and resistance to abiotic and biotic stresses. Marker-assisted selection (MAS) has been instrumental in accelerating the breeding process by enabling the selection of desirable traits based on molecular markers linked to these traits. Additionally, QTL mapping has provided valuable insights into the genetic architecture of complex traits, guiding breeders in the development of high-yielding and nutritionally enhanced wheat varieties. The convergence of these genomic approaches, including GWAS, MAS, and QTL mapping, has ushered in a new era of precision breeding. This review highlights the synergy between these methodologies, illustrating their combined impact on improving wheat biofortification. Future directions in wheat genomics will likely focus on integrating these approaches with emerging technologies, such as CRISPR-based genome editing and advanced phenotyping techniques, to address the challenges of global food security and climate change. The continuous advancement of these genomic tools promises to further enhance the resilience and nutritional quality of wheat, ensuring its pivotal role in global agriculture.