Antiparasitic Efficacy in Canine Sarcoptic Mange: A Comparison Study

Supnesh Jain *

Department of Veterinary Medicine, College of Veterinary Science and A.H., NDVSU, Jabalpur, India.

Ranbir Singh Jatav

Department of Veterinary Medicine, College of Veterinary Science and A.H., NDVSU, Jabalpur, India.

Rupesh Verma

Department of Veterinary Parasitology, College of Veterinary Science and A.H., NDVSU, Jabalpur, India.

Amita Tiwari

Department of Veterinary Medicine, College of Veterinary Science and A.H., NDVSU, Jabalpur, India.

Manoj Patel

Department of Veterinary Medicine, College of Veterinary Science and A.H., NDVSU, Jabalpur, India.

Salil Kumar Pathak

Department of Veterinary Medicine, College of Veterinary Science and A.H., NDVSU, Jabalpur, India.

Aditya Pratap

Department of Veterinary Medicine, College of Veterinary Science and A.H., NDVSU, Jabalpur, India.

Rakesh Dangi

Department of Veterinary Medicine, College of Veterinary Science and A.H., NDVSU, Mhow, India.

Mrinal Singh

Department of Veterinary Medicine, College of Veterinary Science and A.H., NDVSU, Jabalpur, India.

*Author to whom correspondence should be addressed.


Abstract

Sarcoptic mange, caused by Sarcoptes scabiei var. canis, is a highly contagious and zoonotic ectoparasitic infestation affecting dogs worldwide. This study evaluated the occurrence of sarcoptic mange and compared the therapeutic efficacy of selamectin, sarolaner and ivermectin in affected dogs in and around Jabalpur, Madhya Pradesh, India. From May to October 2024, 269 dogs with dermatological affections suspected of sarcoptic mange were examined, with 13 dogs (4.83%) tested positive based on skin scrapings. Age-wise analysis revealed that young dogs (<1 year) exhibited a higher susceptibility to the condition (53.85%). Additionally, male dogs demonstrated a higher occurrence rate (61.54%) compared to females; however, this difference was not statistically significant. A therapeutic trial was conducted on 12 dogs diagnosed with S. scabiei infestations, divided into three treatment groups: Group 1 received ivermectin (0.4 mg/kg PO daily for 28 days), Group 2 received sarolaner (2 mg/kg PO on Day 0), and Group 3 received selamectin (6–12 mg/kg topical spot-on on Day 0). Dermatological signs and mite counts were monitored before and after treatment, including crusting, scaling, erythematous papules and pruritus. Mite counts significantly decreased in sarolaner (100%) and selamectin (100%) treated groups, compared to the ivermectin treated group (26.32%). Sarolaner and selamectin demonstrated superior efficacy in eliminating mites and resolving clinical signs. Sarolaner monthly oral administration and selamectin topical application provide practical, effective options for managing sarcoptic mange, especially for the generalized condition.

Keywords: Sarcoptic mange, sarolaner, selamectin, ivermectin, sarcoptes scabiei


How to Cite

Jain, Supnesh, Ranbir Singh Jatav, Rupesh Verma, Amita Tiwari, Manoj Patel, Salil Kumar Pathak, Aditya Pratap, Rakesh Dangi, and Mrinal Singh. 2025. “Antiparasitic Efficacy in Canine Sarcoptic Mange: A Comparison Study”. Journal of Advances in Biology & Biotechnology 28 (1):728-37. https://doi.org/10.9734/jabb/2025/v28i11928.