Reasons for Hyperhidrosis, Its Effects, and Novel Therapies
Aishwarya ABBURU *
Biomedical Engineering, University of North Texas, Denton, Texas, United States.
Azad RAYAPANENI
Biomedical Engineering, University of North Texas, Denton, Texas, United States.
Praveen RAVULA
Biomedical Engineering, University of North Texas, Denton, Texas, United States.
Rahul Nadigotla
Biomedical Engineering, University of North Texas, Denton, Texas, United States.
*Author to whom correspondence should be addressed.
Abstract
Excessive sweating is a symptom of a long-term medical condition called hyperhidrosis. Despite affecting 2-3% of the global population Millions of people around the world, it is not considered a public health concern. Because of social taboos, patient discomfort, and a general lack of awareness among the medical community, hyperhidrosis is commonly misdiagnosed and undertreated despite its seriousness. The illness has a significant impact on not only physical but also psychological and social well-being, causing disturbances in everyday routines, occupational performance, and interpersonal relationships (Kisielnicka et al., 2022). This report provides an integrated overview of findings from significant investigations, including the underlying pathophysiology, epidemiology, diagnostic approaches, and long-term consequences on quality of life. In certain anatomical areas, it also covers real-world applications and therapeutic experiences, especially with botulinum toxin, iontophoresis, and oral oxybutynin (Lowe et al., 2023).
Keywords: Hyperhidrosis, eccrine sweat glands, aluminum chloride, Iontophoresis, microwave thermolysis, ETS- Endoscopic Thoracic Sympathectomy, sofpironim bromide