An Overview on Leveraging Haplotype-based Genomic Selection for Precision Plant Breeding
B. P. Maruthi Prasad *
University of Agricultural Sciences, Bangalore, India.
M. Pallavi
University of Agricultural Sciences, Bangalore, India.
B. V. Sinchana
University of Agricultural Sciences, Bangalore, India.
J. Harish
University of Agricultural Sciences, Bangalore, India.
K. Sainat
University of Agricultural Sciences, Raichur, India.
*Author to whom correspondence should be addressed.
Abstract
Haplotype-based genomic selection (GS) represents a transformative evolution in the field of precision plant breeding. This methodology integrates haplotypes defined as blocks of DNA variations inherited together with advanced genomic selection frameworks to improve the prediction of complex traits, such as yield and stress resilience. By capturing local epistatic interactions and reducing genotyping costs through efficient marker selection, haplotype-based Genomic selection enhances prediction accuracy and accelerates breeding cycles. This review discusses the foundational principles, methodologies, applications, and future prospects of haplotype-based Genomic selection, emphasizing its critical role in modern plant breeding programs aimed at addressing global food security challenges.
Keywords: Haplotypes, genomic selection, breeding value, tag SNPs, genomic prediction