Therapeutics Activities of Amazonian Plant Himatanthus sucuuba (Spruce ex Müll. Arg.) Woodson (Apocynaceae): A Review
Milene Barbosa da Silva
Federal University of Amazonas, Institute of Biotechnology and Health, Coari/AM, Brazil.
Márcia Pinheiro da Silva
Federal University of Amazonas, Institute of Biotechnology and Health, Coari/AM, Brazil.
José Dobles Dias dos Reis Júnior
Federal University of Amazonas, Institute of Biotechnology and Health, Coari/AM, Brazil.
Carlos Antônio Couto Lima
Department of Health Science, University of Western São Paulo, Presidente Prudente, São Paulo Brazil.
Anderson de Oliveira Souza *
Federal University of Amazonas, Institute of Biotechnology and Health, Coari/AM, Brazil.
*Author to whom correspondence should be addressed.
Abstract
Several compounds extracted from medicinal plants and their active ingredients can relieve symptoms and even cure diseases, although they occasionally have adverse effects. The knowledge of their properties has been transmitted over the centuries within and among human communities. Himatanthus sucuuba is an Amazon plant that has its value attributed to the different herbal impacts popularly reported. This review presents significant biological activities such as antibacterial, antifungal, anthelmintic, antileishmanial, anti-inflammatory, analgesic, antidepressant, immunoregulatory, cytotoxic, and genotoxic. Thus, provides a synopsis of the literature exploring the extracts of H. sucuuba to the Amazon region that could efficiently prevent pathologies associated with leishmaniosis, infection for bacteria or fungus, depression, oxidative stress, and cytotoxicity or genotoxicity.
Keywords: Himatanthus sucuuba, medicinal plants, phytochemistry, plants extracts, biological activities